Current Trends in Mass Spectrometry of Synthetic Polymers

MALDI Mass Spectrometry of Synthetic Polymers

This paper reviews the application of matrixassisted laser desorption/ionization mass spectrometry (MALDI-MS) to the analysis of synthetic polymers, and includes data obtained by Toyota CRDL. In MALDI-MS of synthetic polymers, the selection of a matrix and cationizing agent, as well as the sample preparation techniques, are very important to obtaining a successful spectrum. MALDI-MS makes it po...

Current trends in computational inference from mass spectrometry-based proteomics

Mass spectrometry offers a high-throughput approach to quantifying the proteome associated with a biological sample and hence has become the primary approach of proteomic analyses. Computation is tightly coupled to this advanced technological platform as a required component of not only peptide and protein identification, but quantification and functional inference, such as protein modification...

Review: mass spectrometry of step-growth polymers.

For at least two decades different mass spectrometric techniques have been applied for polymer analysis, including the qualitative determination of chemical compositions, end group identification, functionality type distribution and the determination of the cyclisation extend at each degree of polymerisation. Molecular weights exceeding 100 KDa are provable by MALDI-ToF mass spectrometry. Furth...

Mass spectrometry of polymers and polymer surfaces.

Quantitative Synthetic Polymer Mass Spectrometry Workshop

Mass spectrometry is a rapidly evolving measurement technique for synthetic polymers. It holds the promise of providing not only absolute molecular mass distributions but also quantitative end-group and repeat-unit composition, and structural information such as branching and intramolecular loop formation. It serves as an invaluable complement to size-exclusion chromatography and light scatteri...